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Brevoxyl® Cream

Brevoxyl® Cream


$22.31$17.85  per cream

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Brevoxyl® Cream (Benzoyl Peroxide) 4%, 20 g

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Brevoxyl® Cream is manufactured by Stiefel Laboratories. This is a topical medication developed to treat mild to moderate acne. Brevoxyl® Cream has strong antibacterial and peeling properties. It fights acne-causing germs and unclogs pores by exfoliating dead skin cells. The active substance of this cream is Benzoyl Peroxide (BPO), an organic compound of peroxides class.

Acne is an inflammatory skin disorder caused by an abnormal growth of P. acnes (Propionibacterium acnes) bacteria. P. acnes start proliferating within the clogged pores, and our immune system reacts to this overgrowth with inflammation. Pimples, whiteheads, cysts, non-inflamed comedones, and possible scarring of the breakouts are among the symptoms of acne skin condition.

MOA (mechanism of action):

Benzoyl Peroxide acts as an antibacterial, sebostatic, comedolytic, and anti-inflammatory agent. It is a lipophilic drug, that easily penetrates the outermost layer of the skin (stratum corneum) and enters the pilosebaceous follicle. Then it metabolizes to benzoic acid and hydrogen peroxide and releases free radical oxygen that oxidizes proteins in bacterial cells, exhibiting a bactericidal action towards P. acnes. As an exfoliant, Benzoyl Peroxide increases the turnover rate of epithelial cells and removes dead cells residue from pores, thereby unclogging them and preventing another P. acnes overabundance.


Brevoxyl® Cream is for external use only. Do not apply to your eyes or eyelids, lips, mouth, inside of the nose, private parts, and any other mucosal surface.

Apply Brevoxyl® Cream 1-2 times daily. This cream should be applied for 6-8 weeks at least. Consult your doctor regarding the further use of Brevoxyl® Cream.

In case your acne has not improved after 6-8 weeks of treatment, discontinue the Brevoxyl® Cream use and seek medical advice.

How to use Brevoxyl® Cream:

1. Wash your hands and the affected areas with mild soap or cleanser, pat dry.

2. Apply a thin layer of Brevoxyl® Cream to the areas where you tend to get breakouts, not just to each spot.

3. Rub gently until absorbed.

4. Wash your hands after the cream application.

5. Wait for about 15 minutes and apply a moisturizer or emollient.


If dryness and severe peeling of the skin appear at the start of the Brevoxyl® Cream treatment course, alter the number of daily applications or apply the cream every other day. When the tolerance to the cream is developed, continue your regular application schedule.

During the first week or two of the Brevoxyl® Cream treatment course you may notice a mild burning sensation after the application.

Use sunscreen during the Brevoxyl® Cream treatment course.

As Brevoxyl® Cream makes the skin drier than usual, you should use skin moisturizers during the treatment course.

Do not apply Brevoxyl® Cream to the broken skin, open wounds, cuts or burns (sunburns included).

Be careful while applying Brevoxyl® Cream to sensitive areas like neck.

Missing a dose

If you miss a dose you should take it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule. Do not apply a double dose.


Do not exceed the doctor's recommended dose. If an overdose occurs and you are feeling unwell, you should seek emergency medical attention or contact your healthcare provider immediately.


Store at a room temperature from 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away the tube after the expiration date. Keep away from children.

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Side effects

The most common side effects associated with the use of Brevoxyl® Cream are:

  • dry skin
  • peeling of the skin
  • redness
  • burning sensation
  • itching
  • stinging
  • irritation (irritant contact dermatitis)

Side effects occurrence does not only depend on the medication you are using, but also on your overall health and other factors.


Do not apply Brevoxyl® Cream if you are allergic to Benzoyl Peroxide.

Do not apply Brevoxyl® Cream if you are allergic to any of the other ingredients comprised in Brevoxyl® Cream.

Do not use Brevoxyl® Cream if you are applying any acne treatment containing salicylic acid, retinoids (tretinoin, adapelene, tazarotene, isotretinoin), azelaic acid or sulfone products (dapsone, promin).

Do not use Brevoxyl® Cream if you are taking any medication containing corticosteroids (fluocinolone), benzene derivatives (hydroquinone), phenols (mequinol) or sodium thiosulfate.

Do not use Brevoxyl® Cream if you have asthma or hypersensitivity to benzoic acid or its derivatives (cinnamon, certain topical anesthetics, etc.).

Do not use Brevoxyl® Cream if you have dermatitis, seborrhea, eczema, skin inflammation or damage including sunburn or windburn.

Do not use Brevoxyl® Cream if you are pregnant or breastfeeding without your doctor’s approval.

Do not use Brevoxyl® Cream in patients under the age of 12.

Do not take by mouth. Brevoxyl® Cream is for use only on the skin.

Avoid getting Brevoxyl® Cream on your hair or any colored fabric, as the cream can bleach them.

Do not use Brevoxyl® Cream more than 2 times a day.

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Frequently asked questions

Q: Is Brevoxyl® Cream safe?

A: Brevoxyl® Cream is completely safe as long as used for prescribed condition and at prescribed doses.

Q: Can I use Brevoxyl® Cream for my child?

A: Brevoxyl® Cream can be used in patients older than 12 years of age.

Q: Is it safe to use Brevoxyl® Cream in pregnant women?

A: Although Brevoxyl® Cream is considered as mostly safe for use during pregnancy, you should not start the treatment course without your doctor’s approval.

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Target PointShipping MethodTrackingDelivery TimePrice

Worldwide Shipping

  Not trackable14-21 business days$20.00 per order
  Trackable, where available5-9 business days$30.00 per order

Delivery time is:

Registered Mail - 14-21 business days price - $20.00, no signature is required on delivery.
EMS - 5-9 business days price - $30.00, signature is required on delivery.
Your order will be packed safe and secure and dispatched within 24 hours.

This is exactly how your parcel will look like (pictures of a real shipping item). It has a look of a regular private letter and does not disclose its contents. Size - 9.4x4.3x0.3 inches (24x11x0.7cm).

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